Confirmed by case reports and the development of portable devices, Nanobubble hydrotherapy shows promise in addressing the extreme dryness of Harlequin Ichthyosis by enhancing skin penetration for deeper moisturization, gently exfoliating scales, and potentially improving skin barrier function and reducing infection risks. This therapy offers a novel approach to complement conventional treatments for this severe skin condition. https://pubmed.ncbi.nlm.nih.gov/39371711/
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